अमूर्त

Impact of Computers on Structural Biology of Proteins

Dr Rama Adiga

As more genome sequencing projects are underway on a large scale, more protein sequences are obtained and analysed. The modular units termed protein domains, associate in different ways giving rise to proteins of varied function. In the process of evolution, these combinations have produced many proteins that have new or modified functions. Thus, multidomain proteins are studied to understand the specific or more complex functions. Mutation of the domains potentially reveal disruptions of protein function which is necessary for cancer development.